Growth hormone treatment for growth hormone deficient adults
نویسندگان
چکیده
منابع مشابه
Growth hormone treatment in non-growth hormone-deficient children
Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD). With the availability of unlimited quantities of GH obtained from recombinant DNA technology, researchers started to explore new modalities to treat GHD children, as well as to treat a number of other non-GHD conditions. Although with so...
متن کاملEffect of growth hormone treatment on postprandial protein metabolism in growth hormone-deficient adults.
Growth hormone (GH) treatment of GH-deficient adults increases lean body mass. To investigate this anabolic effect of GH, body composition and postabsorptive and postprandial protein metabolism were measured in 12 GH-deficient adults randomized to placebo or GH treatment. Protein metabolism was measured after an infusion of [1-13C]leucine before and after a standard meal at 0 and 2 mo. After 2 ...
متن کاملOptimization of growth hormone therapy in growth hormone deficient children.
Successful treatment with human growth hormone (hGH) was initially reported by Raben in 19581. Although itis well established that pituitary derived or biosynthetic hGH increases the growth rate in growth hormone deficient children, many patients that were treated in the early days have not reached their target height, or attained adult height below the third percentile of population standards ...
متن کاملMedium and long-term outcome of growth hormone therapy in growth hormone deficient adults.
We evaluated long-term replacement therapy outcomes in various subsets of patients with adult growth hormone (GH) deficiency (AGHD) as well as the patients' susceptibility to adverse events. Fifty-nine patients with AGHD were evaluated, 27 with childhood onset (CO) (18-44 years old, 12 females) and 32 with adult onset (AO) (27-70 years, 18 females). A significant improvement in HDL-cholesterol ...
متن کاملGrowth hormone replacement therapy in growth hormone deficient children and adults: Effects on hemochrome.
Several lines of evidence have suggested a role of the GH/IGF-I axis in the regulation of hemochrome. Many studies have been carried out in GH deficient children and adults about this topic, reporting predominantly a positive effect of recombinant human GH (rhGH) on red series, with no action on serum leucocytes and platelets counts. The aim of this study was to assess the impact of GH deficien...
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ژورنال
عنوان ژورنال: Journal of Clinical Pharmacy and Therapeutics
سال: 1996
ISSN: 0269-4727,1365-2710
DOI: 10.1111/j.1365-2710.1996.tb00034.x